Tuberous Sclerosis. Second Edition

Second Edition McAipine's MULTIPLE SCLEROSIS

Tuberous sclerosis.

Tuberous sclerosis - also called tuberous sclerosis complex (TSC) - is a rare, multi-system genetic disorder affecting cellular differentiation & proliferation, which results in hamartoma formation in many organs. The classic triad of clinical features comprises mental retardation, epilepsy & skin lesion, but these three features are not always present. Mrs. Jahanara Khatun, a 30 years old lady...

tuberous sclerosis

A search for children presenting with signs or symptoms of cardiac rhabdomyomas was made through members of the paediatric section of the British Cardiac Society in order to establish their birth incidence, presenting features, clinical course, and the frequency of a concurrent diagnosis of tuberous sclerosis. Fifteen children were identified and 12 had tuberous sclerosis (80%). Heart failure w...

[Tuberous sclerosis].

Tuberous sclerosis is a multisystem disorder characterized by changes primarily involving the skin, eye, and central nervous system. Although the disease often produces mental retardation and seizures, this is not universal, and some patients with tuberous sclerosis lead a relatively normal life.

Tuberous Sclerosis Alliance

Seizures or epilepsy are common manifestations of tuberous sclerosis. Some 80-90% of individuals with TS have seizure activity during their lifetime, often with onset in childhood. Fortunately, many children and adults with TS have seizure activity that is controlled by medication. After 1-2 years of being seizure free, it is often possible to decrease the use of medications and continue to be ...